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Polymer chemist specialized in physycal chemistry and formulation
Mariana Spulber
,
Niva, Denmark
Experience
Other titles
Skills
I'm offering
Biochemist specialized in polymer chemistry and technology, especially silicon chemistry, with over 12 years research experience in polymer chemistry, polymer materials, formulation chemistry, especially colloids and self-assembly, physical chemistry and fuel cells. Experience on the laboratory and pilot scale in product and process development, up-scaling and quality control.
Markets
Denmark
Links for more
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Language
English
Fluently
French
Fluently
Ready for
Larger project
Ongoing relation / part-time
Full time contractor
Available
My experience
2017 - ?
job
Formulation Scientist, Department of Formulation and Scale up
FMC.
Denmark
Developing new formulations based on pre-formulation experiments input in accordance with product requirements;
o Design, optimization and characterization (CIPAC methods) of liquid and solid formulations with biological AI according to the market specifications.
o Up scaling of developed formulations and long-term stability testing according with CIPAC
methods.
o Verify and write final activity reports.
Raw materials management;
o Supply chain management of all raw materials for the formulation in accordance with
required specifications imposed by FDA and OMRI. Identifying organic alternatives for the formulations developed with compounds feasible from economical and availability point of view.
o Identify potential strategies and develop a database for a certain type of formulation and a specific bio-pesticide. Check how to develop faster formulations with different bio-pesticides by applying the strategies developed in the framework of the database.
o Technical support for formulation currently in production.
Safety;
o Maintain zero record of safety incidents category 1 and 2 by reading and/or improving the written instructions of operating different equipment in the lab and manipulation of different
solvents.
o Create APBs (chemical risk assessment) for the chemicals existing in the laboratories or
storage.
Developing new formulations based on pre-formulation experiments input in accordance with product requirements;
o Design, optimization and characterization (CIPAC methods) of liquid and solid formulations with biological AI according to the market specifications.
o Up scaling of developed formulations and long-term stability testing according with CIPAC
methods.
o Verify and write final activity reports.
Raw materials management;
o Supply chain management of all raw materials for the formulation in accordance with
required specifications imposed by FDA and OMRI. Identifying organic alternatives for the formulations developed with compounds feasible from economical and availability point of view.
o Identify potential strategies and develop a database for a certain type of formulation and a specific bio-pesticide. Check how to develop faster formulations with different bio-pesticides by applying the strategies developed in the framework of the database.
o Technical support for formulation currently in production.
Safety;
o Maintain zero record of safety incidents category 1 and 2 by reading and/or improving the written instructions of operating different equipment in the lab and manipulation of different
solvents.
o Create APBs (chemical risk assessment) for the chemicals existing in the laboratories or
storage.
Design, Database, Supply chain management, Management, Supply Chain Management, Support, Testing, Safety, Ai, Assessment, SOLID, Storage, Production, Framework, Formulation, UP
2015 - 2017
job
Head of Formulation Department
Aquaporin A/S.
Denmark
Developing new formulations based on pre-formulation experiments input in accordance with product requirements.
o Design and produced colloidal based polymer/protein hybrid materials for increased water
flux reverse and forward osmosis membranes. 10 different polymer categories (polysilicones, polyethylene oxide, polystyrene based copolymers, etc) and various surfactants neutral and ionic have been sucessfuly employed and 4 patent applications have been filed.
o Polymer purification and chemical modification to ensure higher thermal stability and pH
behavior of produced formulations
o Supply chain management of all raw materials for the formulation in accordance with required specifications imposed by FDA
o Up-scaling to 100 and 500 L volumes
o Quality control and development of physical characterization methods of the formulations
Project management of two projects initiated for technical transfer to joined venture in China
o Planning of the required actions, specific documentation and budget
o Stakeholder management
o Risk management analysis
o Communication between different stakeholders
o Reporting
Group management
o Assign specific tasks
o Verify and write final activity reports
o Personal responsibilities and salary negotiations
o I managed a 4 persons group
Developing new formulations based on pre-formulation experiments input in accordance with product requirements.
o Design and produced colloidal based polymer/protein hybrid materials for increased water
flux reverse and forward osmosis membranes. 10 different polymer categories (polysilicones, polyethylene oxide, polystyrene based copolymers, etc) and various surfactants neutral and ionic have been sucessfuly employed and 4 patent applications have been filed.
o Polymer purification and chemical modification to ensure higher thermal stability and pH
behavior of produced formulations
o Supply chain management of all raw materials for the formulation in accordance with required specifications imposed by FDA
o Up-scaling to 100 and 500 L volumes
o Quality control and development of physical characterization methods of the formulations
Project management of two projects initiated for technical transfer to joined venture in China
o Planning of the required actions, specific documentation and budget
o Stakeholder management
o Risk management analysis
o Communication between different stakeholders
o Reporting
Group management
o Assign specific tasks
o Verify and write final activity reports
o Personal responsibilities and salary negotiations
o I managed a 4 persons group
UP, Formulation, Hybrid, Protein, Planning, Patent, China, Development, Design, Ionic, Management, Supply chain management, Risk Management, Stakeholder Management, Budget, Project Management
2012 - 2015
job
Research associate
University of Basel, Department of Physical Chemistry.
Basel
RD tasks
o Polymer synthesis and purification. Correlation between the chemical structure and supramolecular properties, auto-assembling and molecular recognition.
o Colloidal systems design and production. Functional protein reconstitution.
o EPR specialist (spin trapping, free radicals detection, metal catalytic centers characterization)
All projects were finalized in 25 publications in international scientific journals.
Project management
oSupervised 3 master thesis and 2 bachelor theses.
Teaching
o Organized the physical chemistry practical course
RD tasks
o Polymer synthesis and purification. Correlation between the chemical structure and supramolecular properties, auto-assembling and molecular recognition.
o Colloidal systems design and production. Functional protein reconstitution.
o EPR specialist (spin trapping, free radicals detection, metal catalytic centers characterization)
All projects were finalized in 25 publications in international scientific journals.
Project management
oSupervised 3 master thesis and 2 bachelor theses.
Teaching
o Organized the physical chemistry practical course
Design, Project Management, Research, Teaching, Management, Chemistry, International, Production, Protein
2009 - 2012
unknown
Guest host chemistry investigation by spin probe EPR
Post-doctoral fellowship.
Detroit, Michigan
RD activities
o EPR study of the degradation processes of the perfluorinated membranes for fuel cell design.
o Spin trapping
o Guest host chemistry investigation by spin probe EPR
Project Supervision
o Supervised 2 bachelor theses.
RD activities
o EPR study of the degradation processes of the perfluorinated membranes for fuel cell design.
o Spin trapping
o Guest host chemistry investigation by spin probe EPR
Project Supervision
o Supervised 2 bachelor theses.
Design, Chemistry, Supervision, Processes
2004 - 2009
job
Research associate
"Petru Poni" Institute of Macromolecular Chemistry.
Iasi, Inorganic Polymers Department
Polymer synthesis, purification and characterization
o Synthesis and purification of polysiloxanes and polysilanes structural characterization
o Polysilanes and polysiloxanes modification by click chemistry for surface engineering
Formulation of hydrophobic drugs by host guest chemistry
o Host guest chemistry of specific antifungal drugs with cyclodextrins, determination of the minimal inhibitory dose and acute toxicity studies.
Polymer synthesis, purification and characterization
o Synthesis and purification of polysiloxanes and polysilanes structural characterization
o Polysilanes and polysiloxanes modification by click chemistry for surface engineering
Formulation of hydrophobic drugs by host guest chemistry
o Host guest chemistry of specific antifungal drugs with cyclodextrins, determination of the minimal inhibitory dose and acute toxicity studies.
Research, Chemistry, Engineering, Formulation
My education
2014
-
2019
Institute of Macromolecular Chemistry
Doctorate, N/a
Doctorate, N/a
more specifically Host guest chemistry of specific antifungal drugs with cyclodextrins, determination of the minimal inhibitory dose and acute toxicity studies.
2012
-
2014
Babes Bolyai University
Masters, Plant Genetic Engineering MSc
Masters, Plant Genetic Engineering MSc
1998
-
2002
Al I Cuza University Iasi
BSc, Biology-Biochemistry
BSc, Biology-Biochemistry
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